Recently, I came across a paper in reputed weekly chemistry journal, Tetrahedron Letters. It was describing short synthesis of Noscapine and some other natural alkaloids. However, while carefully looking at the structure I found that they have synthesized a molecule which is not Noscapine. When I did a SciFinder investigation for the same I confirmed … Read more
Chemical Abstract Services (CAS) has announced that it will discontinue to support the desktop client version of the SciFinder. It means that everyone intending to use SciFinder on campus or off-campus need to have their own username and password to access SciFinder services via its web interface. The client service can be used in its … Read more
The Winners of Noble Prize in Chemistry are being announced at 11:45 AM CET (Central European Time) on Wednesday, 10th October 2012. The prize will be announced by Staffan Normark, Permanent Secretary of the Royal Swedish Academy of Sciences Nominations & Selection: Nomination to the Nobel Prize in Chemistry is by invitation only. The Nobel Committee … Read more
Since the development of the Pro-drug strategy for the anti viral nucleosides for the treatment of HIV by Christopher McGuigan in 1993, there have been various attempts in designing a reagent for the chiral pro drug synthesis. Since the market debut of Gilead’s Blockbuster drug the reagent (shown as Chiral reagent in the graphics below) … Read more