This compound is obtained by the reaction of DMTCl with Thymidine under Pyridine. I tried to avoid the Pyridine and used 1,4-Dioxane instead, with catalytic amount of the DMAP. Everything was Ok, I was planning to make slurry to purify it.
Image via Wikipedia Noscapine is an isoqiunoline alkaloid found in opium latex. Unlike most other alkaloids obtained from opium latex, noscapine is not sedative and has been used as antitussive drug in various countries. Recently, it has been introduced as an anti-mitotic agent. This drug can be used orally.When the resistance to other anti-cancer drugs … Read more
Carbocyclic Nucleosides is the name given to the class of molecules which are very similar to Nucleosides despite the fact that their furanose ring system in sugar counterpart is replace by a cyclopentyl ring. The first molecule, classified as Carbocyclic Nucleoside was Synthesized in a lab of Southern Research Institute in Birmingham, Albama. It was … Read more
