[warning]In the last decade, a number of carbocyclic nucleoside analogs have been reported to posses interesting anti viral and anti cancer properties. We have communicated an article with the aforesaid title which would be available soon.[/warning]
The review article titled “Discovery and Development of Anti-HBV Agents and Their Resistance” is open access and can be downloaded by clicking the link on preview image of the article.
Image via Wikipedia Influenza viruses are a group of RNA viruses from Orthomyxoviridae family. These are 3 in number namely: Influenzavirus A, Influenzavirus B and Influenzavirus C. Each of these genus has only one species namely influenza A virus, influenza B virus and influenza C virus. Among the three, type A causes severe disease and … Read more
Design & Development of Unnatural Nucleosides as Antiviral & Anti-Cancer Agents Ram C. Mishra College of Pharmacy, University of Georgia, GA 30602, USA Unnatural nucleosides are the variants (chemically modified analogs) of five natural nucleosides which constitute the structure of DNA and RNA. Since the first preparation and later, the isolation of unnatural … Read more
Recently (December 6th, 2013) Sofosbuvir was approved by US FDA for the treatment of Chronic Hepatitis C in combination with Ribavirin for dual therapy and with Ribavirin & Pegylated Interferon triple therapy for treatment-naive patients having HCV genotypes 1 and 4. The drug is being marketed as Sovaldi by Gilead.