Image via Wikipedia Noscapine is an isoqiunoline alkaloid found in opium latex. Unlike most other alkaloids obtained from opium latex, noscapine is not sedative and has been used as antitussive drug in various countries. Recently, it has been introduced as an anti-mitotic agent. This drug can be used orally.When the resistance to other anti-cancer drugs … Read more
Anticancer chemotherapy using targets amenable by nucleoside drugs: There are some recently discovered targets where compounds of ‘nucleoside’ class or just the ‘Nucleosides’ have shown some interesting biological effects. Most of these could be modulated to get novel nucleoside based highly targeted therapy of various cancer sub types.
[warning]In the last decade, a number of carbocyclic nucleoside analogs have been reported to posses interesting anti viral and anti cancer properties. We have communicated an article with the aforesaid title which would be available soon.[/warning]
A new anticancer drug for Leukemia has been approved by FDA. The drug treats chronic myelogenous leukemia (CML), a blood and bone marrow disease that usually affects seniors. It works by inhibiting the enzyme Tyrosine Kinase.
Design & Development of Unnatural Nucleosides as Antiviral & Anti-Cancer Agents Ram C. Mishra College of Pharmacy, University of Georgia, GA 30602, USA Unnatural nucleosides are the variants (chemically modified analogs) of five natural nucleosides which constitute the structure of DNA and RNA. Since the first preparation and later, the isolation of unnatural … Read more